PerioTrap Pharmaceuticals GmbH
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Dr. James Belcher, December 13, 2025
Your gums and your heart have more in common than you might think. Researchers are uncovering increasing evidence that periodontitis – chronic gum inflammation – not only endangers teeth but can also contribute to heart attacks and strokes. Sound alarming? Don't worry – this article explains why and what you can do to protect yourself.
Periodontitis is a chronic inflammation of the gums and supporting structures of the teeth – triggered by an imbalance in the oral microbiome. Bacteria such as Porphyromonas gingivalis (P. gingivalis) can attack the gums, cause inflammation, and in advanced stages lead to gum recession and tooth loss.
Periodontitis doesn't just affect the mouth – inflammatory substances and bacteria can enter the bloodstream through the gums. :contentReference[oaicite:3]{index=3}
If this chronic inflammation is left untreated, the risk of cardiovascular disease increases significantly: those affected have an elevated risk of heart attack, stroke, or other vascular diseases. :contentReference[oaicite:5]{index=5}
Studies show that in periodontitis, inflammatory markers in the body rise – this can lead to damage to blood vessel walls, inflammation, and in the worst case, the promotion of arteriosclerotic processes (hardening of the arteries). :contentReference[oaicite:6]{index=6}
Researchers were also able to detect bacteria from diseased gums in atherosclerotic vascular plaques. :contentReference[oaicite:7]{index=7}
A large systematic review in 2023 concluded that there is a significant correlation between periodontitis and cardiovascular disease. :contentReference[oaicite:8]{index=8}
People with severe periodontitis have a significantly increased risk of cardiovascular disease compared to people with healthy oral flora. :contentReference[oaicite:9]{index=9}
European Society of Cardiology (2023); Journal of Clinical Periodontology (2022); Systematic Review I. Etta et al. (2023); Specialist literature on periodontitis and cardiovascular diseases. :contentReference[oaicite:10]{index=10}