What is periodontitis?

Periodontitis is a chronic inflammation of the gums, triggered by an imbalance in the oral microbiome (the community of microorganisms in your mouth). Certain bacteria, most notably Porphyromonas gingivalis (P. gingivalis), can attack the gums, cause deep periodontal pockets, and ultimately lead to tooth loss.

Why is the connection to Alzheimer's disease important?

Periodontitis doesn't just affect the mouth. The bacteria and their gingipains (enzymes that break down tissue) can enter other organs via the bloodstream. Research shows that P. gingivalis and its toxins have been found in the brains of Alzheimer's patients. This suggests that chronic gum inflammation not only accompanies Alzheimer's but may also contribute to its development.

Science explained briefly

Scientists discovered that P. gingivalis produces so-called virulence factors – tools the bacterium uses to trick immune cells and destroy tissue. Studies showed that mice infected with P. gingivalis developed similar protein deposits (amyloid plaques) in the brain as Alzheimer's patients. At the same time, researchers confirmed that blocking bacterial activity – as with PerioTrap® technology – reduces the toxic effects of P. gingivalis without disturbing the beneficial bacteria in the mouth.

What can you do?

• Thorough oral hygiene: Brush twice a day, use dental floss or interdental brushes.
• Go for regular preventative care: Professional teeth cleaning removes stubborn plaque.
• Take early signs seriously: bleeding gums or bad breath can be warning signals.
• Use targeted products: Products like PerioTrap Microbiome Toothpaste support your gums by blocking harmful bacteria and promoting a healthy microbiome.

In summary

• Periodontitis bacteria can migrate to the brain.
• P. gingivalis is suspected of promoting Alzheimer's disease.
• PerioTrap products provide targeted protection for gums and the microbiome.

Did you know?

Alzheimer's disease is the most common form of dementia – and studies show that people with severe periodontitis have up to a 70% higher risk of developing it.

Sources

Dominy SS et al. “Porphyromonas gingivalis in Alzheimer's disease brains” (Science Advances, 2019); PerioTrap AI Documentation & Flyer (2024-2025); Kamer AR et al. “Periodontal disease and risk for Alzheimer's disease” (Neurology, 2008)