What is that?

Microbiome modulation is an approach to oral care that doesn't "wipe out" everything, but rather intervenes in a targeted way. Your mouth is home to over 700 different types of bacteria. Many of them are beneficial – they protect you from pathogens and strengthen your gums.

Conventional products like strong mouthwashes or broad-spectrum antibiotics kill all bacteria indiscriminately. This disrupts the balance – experts refer to this as dysbiosis. As a result, harmful germs can recolonize more quickly, increasing the risk of inflammation.

Why is it important?

A stable oral microbiome acts like a natural protective shield. If it becomes unbalanced, not only gum inflammation (gingivitis) and periodontitis can result. Studies show that a disrupted oral flora may be linked to diseases such as diabetes, cardiovascular disease, and possibly even Alzheimer's.

The future of dentistry therefore lies in specifically blocking pathogens such as Porphyromonas gingivalis – and simply letting the good bacteria fulfill their protective function.

Science explained briefly

PerioTrap researchers have developed a molecule called S-0636 that acts as a so-called pathoblocker. It does not kill P. gingivalis, but rather disables its disease-causing mechanisms – for example, the production of aggressive enzymes that attack tissue.

This means: no classic resistance development and no harm to beneficial bacteria. In laboratory studies, biofilm mass could be reduced by up to 25% – without disrupting the microbiome.

What can you do?

• Use mild toothpastes that don't sterilize but protect your microbiome.
• Avoid using unnecessarily strong antiseptics in everyday life – they belong more in short-term therapy at the dentist.
• Look for products with a selective effect, for example the PerioTrap microbiome toothpaste, which focuses on targeted blockage, promotes the balance of your microbiome and protects your gums in the long term.

In summary

• “Everything-killing” approaches disrupt your microbiome.
• Selective blockade protects the good bacteria and only takes away the "weapons" of the harmful ones.
• PerioTrap shows: The future of oral care is microbiome modulation.

Did you know?

Chlorhexidine, a commonly used antiseptic, can discolor teeth and alter the sense of taste – and also destroys many of your good bacteria.

Sources

• Studies & Materials from PerioTrap Pharmaceuticals
• Fraunhofer IZI-MWT
• Scientific literature on P. gingivalis and microbiome research